My Wishlist

FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)

Add to wishlistAdded to wishlistRemoved from wishlist 0
Add to compare
Add your review
Product is rated as #5 in category Flea & Tick
9.4
Set Lowest Price Alert
×
Notify me, when price drops
Set Alert for Product: FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box) - $34.83

$34.83

Best deal at: amazon.comAmazon.com
Buy for best price
  • Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
  • Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
  • Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
  • Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations.
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.
Last updated on August 2, 2026 7:02 am

FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)
FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)

Price History

Price history for FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)
Latest updates:
  • $34.83 - July 23, 2026
  • $40.98 - July 7, 2026
  • $35.34 - June 29, 2026
  • $24.39 - June 27, 2026
  • $27.25 - June 25, 2026
  • $30.04 - June 23, 2026
  • $40.98 - June 15, 2026
  • $35.34 - June 11, 2026
Since: May 12, 2026
  • Highest Price: $40.98 - June 10, 2026
  • Lowest Price: $24.39 - June 27, 2026

Description

From the manufacturer

Smiling man playing fetch outside with healthy dog free from fleas & ticks thanks to Frontline Plus
Frontline Plus has been trusted by pet owners for over 20 years and kills fleas and chewing lice
Answers to frequently asked questions about Frontline flea and tick prevention and treatment plans

How to Apply FRONTLINE Plus for Dogs

Step one woman reading instructions on pack before applying flea and tick non prescription treatment

{
“@context”: “https://schema.org”,
“@type”: “Product”,
“name”: “FRONTLINEu00ae Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)”,
“description”: “Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, “,
“url”: “https://www.pupperbrand.com/product/frontline-plus-for-dogs-flea-and-tick-treatment-small-dog-5-22-lbs-3-doses-orange-box/”,
“brand”: {
“@type”: “Brand”,
“name”: “Pupper Brand”
},
“image”: “https://www.pupperbrand.com/wp-content/uploads/2023/08/frontline-plus-flea-and-tick-treatment-for-medium-dogs-up-to-23-to-44-lbs-3.jpg”,
“offers”: {
“@type”: “Offer”,
“url”: “https://www.amazon.com/dp/B00008DFGY?tag=pupperbrand-20”,
“priceCurrency”: “USD”,
“price”: “49.99”,
“availability”: “https://schema.org/InStock”,
“seller”: {
“@type”: “Organization”,
“name”: “Amazon”
}
}
}

{
“@context”: “https://schema.org”,
“@type”: “Product”,
“name”: “FRONTLINEu00ae Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)”,
“description”: “Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, “,
“url”: “https://www.pupperbrand.com/product/frontline-plus-for-dogs-flea-and-tick-treatment-small-dog-5-22-lbs-3-doses-orange-box/”,
“brand”: {
“@type”: “Brand”,
“name”: “Pupper Brand”
},
“image”: “https://www.pupperbrand.com/wp-content/uploads/2023/08/frontline-plus-flea-and-tick-treatment-for-medium-dogs-up-to-23-to-44-lbs-3.jpg”,
“offers”: {
“@type”: “Offer”,
“url”: “https://www.amazon.com/dp/B00008DFGY?tag=pupperbrand-20”,
“priceCurrency”: “USD”,
“price”: “49.99”,
“availability”: “https://schema.org/InStock”,
“seller”: {
“@type”: “Organization”,
“name”: “Amazon”
}
}
}

Step two woman holding applicator upright and away from her face before opening by snapping off tip

Step three prep dog for flea treatment application by using fingers to part fur so skin is visible

Step four place the open applicator to dogs skin and squeeze out all contents on dog

Read full instructions on packaging before use. Shown here: Size Large 45-88 lbs.

Use scissors to separate one blister. Hold applicator upright with foil side toward you and snap applicator tip off.

Part dog’s hair between shoulder blades until skin is visible.

Place applicator tip directly against exposed skin and apply entire contents directly to the skin. Do not apply on top of hair.

Pack of Frontline Plus for small dog breeds tratamiento de pulgas y garrapatas para perros pequenos Pack of Frontline Plus for medium dog breeds medicina para matar pulgas y garrapatas Pack of Frontline Plus for large dog breeds prevención de pulgas y garrapatas para perros grandes Pack of Frontline Plus for xl dog breeds control de pulgas y garrapatas para perros extra grandes Frontline Plus Cat
FRONTLINE Plus for Small Dogs FRONTLINE Plus for Medium Dogs FRONTLINE Plus for Large Dogs FRONTLINE Plus for X-Large Dogs FRONTLINE Plus for Cats
Recommended pet size 5 to 22 pounds 23 to 44 pounds 45 to 88 pounds 89 to 132 pounds Cats and kittens over 1.5 pounds
Kills adult fleas, flea eggs, and flea larvae
Kills ticks and chewing lice
Minimum age of pet for use Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Cats and kittens 8 weeks and older
Available sizes 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose
Do not use on cats Do not use on cats Do not use on cats Do not use on cats For use on cats only

Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE®. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog’s entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: *Data on file at Boehringer Ingelheim. **Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

Additional information

Specification: FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)

Condition

New: A brand-new, unused, unopened, undamaged item. See the seller's listing for full details. See all condition definitionsopens in a new window or tab

UPC

Brand

Type

FRONTLINE

Dog Size

, ,

EPA Registration Number

Life Stage

Dog Weight

5 to 22 lbs.

Model

FRONTLINE Plus

MPN

FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box) Videos

YouTube

Reviews (0)

User Reviews

0.0 out of 5
0
0
0
0
0
Write a review

There are no reviews yet.

Be the first to review “FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)”

Your email address will not be published. Required fields are marked *

Pupper Brand
Logo
Compare items
  • Total (0)
Compare
0